Connecting minds.

Why Synaption

Technology that supports the clinician. It does not replace them.

Many psychiatric and neurodevelopmental assessments still rely mostly on interviews and rating scales. We are researching whether EEG can add an objective signal to that process, and we publish what we find, including what does not work yet.

  • Scientific rigour

    Leave-one-subject-out validation and audited pipelines. When we found leakage in our own results, we corrected the numbers in public.

  • Ethics and transparency

    Every result is shown with the dataset, age range and method behind it. Nothing is presented as a diagnosis.

  • Open science

    Parts of our tooling are open source, so others can check the methods and reuse them.

How it works

From raw EEG to a report a clinician can question

  1. 01

    Recording

    An EEG recording is uploaded to the platform as an EDF file.

  2. 02

    Signal processing

    Filtering, epoching and automatic cleaning of noisy segments with MNE-Python and AutoReject.

  3. 03

    Feature extraction

    Spectral power, band ratios, coherence between channels and complexity measures.

  4. 04

    Decision-support report

    A calibrated probability with the features that drove it (SHAP), for the clinician to review.

Read the full methodology

The SynapCore platform

Five modules, one platform

All modules are in research and development. None is approved for clinical diagnostic use.

Neuraxis

ADHDResearch Use Only

EEG biomarker analysis to support ADHD assessment. The most advanced SynapCore module, with preliminary results in a paediatric cohort.

Explore Neuraxis
0.650
AUC, children 7 to 12
0.595
Balanced accuracy
LOSO
Leave-one-subject-out, IEEE ADHD dataset
Adults
Under revalidation, ages 18 to 35

Preliminary research results. Not available for clinical use.

  • Lumia Neuro

    In development
    Depression

    Frontal alpha asymmetry and coherence measures to support assessment of major depressive disorder.

  • PsycheVox

    In development
    Schizophrenia

    Gamma band and auditory ERP markers for schizophrenia spectrum evaluation.

  • Equinox

    In development
    Bipolar disorder

    Resting-state power spectral profiles to help tell bipolar states apart.

  • Serenex

    In development
    PTSD

    Theta oscillation and hyperarousal markers for PTSD decision support.

Where we are

An honest view of our current stage

We would rather show modest, reproducible numbers than impressive ones that do not hold up.

Status
Pre-commercial, Research Use Only
Regulatory
Not UKCA, CE marked or FDA cleared. Not for clinical use.
Data
Retrospective work on public EEG datasets. No patient data yet.
Open source
syntony, tidyeeg and clinical-rag-workflow on GitHub

Working in EEG research or clinical neuroscience?

We are looking for research and clinical partners to help validate SynapCore.